Useful Immunohistochemical Markers of Tumor Differentiation

Prognostic factors in phyllodes tumor of the breast: are immunohistochemical biomarkers useful?

Plants as useful agents for angiogenesis and tumor growth prevention

Introduction: Angiogenesis, the process of new blood vessel formation from pre-existing vessels, has important physiological roles in embryonic development, female reproduction cycle, and wound healing. It is also crucial for pathological processes in several diseases especially tumor growth and metastasis. Thereby, inhibition of angiogenesis as an addition to the conventional therapies such...

Immunohistochemical Identification of Arteriolar Development Using Markers of Smooth Muscle Differentiation

Arteriolar growth is an important event in the adaptation of normal tissues as well as in important pathologies, but the site of origin of new arterioles remains unknown. The network pattern of arteriolar development in skeletal muscle was detected by use of a new immunohistochemical technique that is based on the observation that fully differentiated (mature) vascular smooth muscle (SM) cells ...

Perineural cell differentiation in ganglioneuromas. Report of 8 cases with immunohistochemical expression of perineural cell markers.

Eight cases of ganglioneuroma were examined for a presence of perineural cell differentiation, using the immunohistochemical markers epithelial membrane antigen (EMA), claudin-1 and GLUT-1. The mean age of the patients was 42.3 years (range 26-68 years), six patients were females and two were males. Five tumors were located in the adrenal gland and 3 tumors in the retroperitoneum. Morphology of...

Mesothelial Differentiation, Mesothelioma and Tumor Markers in Serous Cavities

Mesothelial cells covering the serous membranes are of mesodermal origin although they acquire several characteristics of epithelial cells. The cytological and histological diagnosis of malignant tumors in serous cavities is sometimes a major challenge: the main diagnostic alternatives are reactive benign mesothelium, mesothelioma and adenocarcinoma. The aims of this thesis were to improve the ...